Tags: Trench fever

Bartonella

Essentials of Diagnosis • Key signs and symptoms include dermal lesion (bacillary angiomatosis and chronic phase of Bartonella bacilliformis infection); papule at inoculation site followed by proximal lymphadenopathy (cat scratch disease); fever, bacteremia, acute hemolytic anemia (acute phase of B bacilliformis infection); persistent or relapsing fever (fever and bacteremia/endocarditis). • Predisposing factors include louse exposure, low income, and homelessness (Bartonella quintana-associated bacillary angiomatosis, fever, and bacteremia/endocarditis); cat exposure (cat scratch disease and Bartonella henselae-associated bacillary angiomatosis, fever and bacteremia/endocarditis); sandfly exposure in endemic areas of South American Andes (B bacilliformis infection). • History of HIV or immunocompromise (bacillary angiomatosis). • Key laboratory findings include small, curved, pleomorphic weakly gram-negative bacilli, best …

Continue Reading...

Fever & Bacteremia/Trench Fever/Endocarditis

The four Bartonella species that are pathogenic for humans are capable of causing sustained or relapsing bacteremia accompanied by only fever (Table 1). All except B bacilliformis also cause endocarditis. After B quintana enters the body through broken skin from the excreta of the infected human body louse (Pediculus humanus), there is an incubation period of between 5 and 20 days before the onset of trench fever. Patients complain of fever, myalgias, malaise, headache, bone pain — particularly of the legs, and a transient macular rash. Usually the illness continues for 4-6 weeks. Sustained or recurrent bacteremia is common, with or without symptoms. The form of trench fever described in the …

Continue Reading...

Bartonella Infections

Description of Medical Condition Bartonella infections cause manifestations in two broad categories: • Localized skin lesions and prominent regional lymphadenitis, i.e., typical cat scratch disease (CSD). Atypical CSD manifestations often represent disseminated infection. • Primary bacteremia, potential for persistent disseminated infection with localized inflammatory (and neovascular) lesions in a variety of organ systems and/or ongoing bacteremia. System(s) affected: Nervous, Cardiovascular, Musculoskeletal, Pulmonary, Gastrointestinal, Skin/ Exocrine, Hemic/Lymphatic/lmmunologic Genetics: No defined genetic predisposition Incidence/Prevalence in USA: • Non-B. bacilliformis infections: – CSD: estimated 9.3/100,000 people (approximately 25,000 cases annually) • Others, no incidence estimates Predominant age: • B. henselae infections: – CSD: 55% in persons < 18 years old – BA/BP, bacteremia, endocarditis, …

Continue Reading...

Tetracyclines General Statement: Uses

Tetracyclines are used principally in the treatment of infections caused by susceptible Rickettsia, Chlamydia, Mycoplasma, and a variety of uncommon gram-negative and gram-positive bacteria. Because of the development of resistance, tetracyclines are rarely used for the treatment of infections caused by common gram-negative or gram-positive bacteria unless other appropriate anti-infectives are contraindicated or are ineffective and in vitro susceptibility tests indicate that the causative organisms are susceptible to the drugs. Generally, given a susceptible organism, the currently available tetracyclines are all equally effective when administered in appropriate dosages. Because minocycline and, to a lesser extent, doxycycline penetrate most body tissues and fluids better than do other currently available tetracyclines, some clinicians …

Continue Reading...

Buy Azithromycin (Zithromax) Without Prescription 250/500mg

Azithromycin • Azithromycin is a semisynthetic azalide antibiotic, a subclass of macrolide antibiotics, with a broader spectrum than that of erythromycins or clarithromycin. Uses Azithromycin is used orally in adults for the treatment of mild to moderate upper and lower respiratory tract infections and uncomplicated skin and skin structure infections caused by susceptible organisms. Oral azithromycin also is used for the treatment of urethritis or cervicitis caused by Chlamydia trachomatis or Neisseria gonorrhoeae, and for the treatment of chancroid caused by Haemophilus ducreyi. Azithromycin is used orally for the treatment of disseminated infections caused by Mycobacterium avium complex (MAC) in patients with human immunodeficiency virus (HIV) infection and for prevention of …

Continue Reading...

Order Ilosone (Erythromycin) No Prescription 250\500mg

Erythromycin • Erythromycins are macrolide antibiotics that are active principally against gram-positive cocci and bacilli and to a lesser extent gram-negative cocci and bacilli; the drugs also exhibit activity against chlamydia, mycoplasma, ureaplasma, spirochetes, and mycobacteria. Uses Prior to initiation of erythromycin therapy, appropriate specimens should be obtained for identification of the causative organism and in vitro susceptibility tests. Use of erythromycin does not preclude the necessity for surgical procedures (such as incision and drainage) as needed. There does not appear to be a difference in clinical efficacy among the erythromycin derivatives when each is administered in appropriate doses. However, some clinicians believe that the risk of hepatotoxicity from the estolate …

Continue Reading...

Ceftriaxone Sodium

• Ceftriaxone is a semisynthetic, third generation cephalosporin antibiotic. Uses Ceftriaxone is used for the treatment of bone and joint infections, endocarditis, intra-abdominal infections, meningitis and other CNS infections, otitis media, respiratory tract infections,septicemia, skin and skin structure infections, and urinary tract infections caused by susceptible bacteria. The drug also is used for the treatment of chancroid, gonorrhea and associated infections, pelvic inflammatory disease,infections caused by Neisseria meningitidis, infections caused by Shigella, and typhoid fever and other infections caused by Salmonella. In addition, ceftriaxone is used for the treatment of Lyme disease and for empiric anti-infective therapy in febrile neutropenic patients, and has been used for perioperative prophylaxis. Ceftriaxone has a …

Continue Reading...

Order Erythromycin (Ilosone) Without Prescription 250/500mg

Erythromycin [Ilosone 250mg, 500mg] (British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Eritromicin; Eritromicina; Eritromicinas; Erythromycin; Erythromycinum; Erytromycin; Erytromysiini BAN: Erythromycin INN: Erythromycin [rINN (en)] INN: Eritromicina [rINN (es)] INN: Érythromycine [rINN (fr)] INN: Erythromycinum [rINN (la)] INN: Еритромицин [rINN (ru)] Chemical name: Erythromycin A is (2R,3S,4S,5R,6R,8R,10R,11R,12S,13R)-5-(3-amino-3,4,6-trideoxy-N,N-dimethyl-β-d-xylo-hexopyranosyloxy)-3-(2,6-dideoxy-3-C,3-O-dimethyl-αl-ribo-hexopyranosyloxy)-13-ethyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethyl-9-oxotridecan-13-olide Molecular formula: C37H67NO13 =733.9 CAS: 114-07-8 ATC code: D10AF02; J01FA01; S01AA17 Read code: y00zu [Skin]; y02P4; y0Cdx [2] Pharmacopoeias. In China, Europe, International, Japan, and US. European Pharmacopoeia, 6th ed., 2008 and Supplements 6.1 and 6.2 (Erythromycin). It is produced by the growth of a strain of Streptomyces erythreus and …

Continue Reading...

Buy Sumycin (Tetracycline) Without Prescription 250/500mg

Tetracycline [Sumycin 250mg, 500mg] (British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Tetraciclina; Tetraciklin; Tetraciklinas; Tetracyclinum; Tetracyklin; Tetrasykliini BAN: Tetracycline INN: Tetracycline [rINN (en)] INN: Tetraciclina [rINN (es)] INN: Tétracycline [rINN (fr)] INN: Tetracyclinum [rINN (la)] INN: Тетрациклин [rINN (ru)] Chemical name: A variably hydrated form of (4S,4aS,5aS,6S,12aS)-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide Molecular formula: C22H24N2O8 =444.4 CAS: 60-54-8 (anhydrous tetracycline); 6416-04-2 (tetracycline trihydrate) ATC code: A01AB13; D06AA04; J01AA07; S01AA09; S02AA08; S03AA02 Read code: y00qJ [Mouth]; y02NR; y08DH [Systemic] Pharmacopoeias. In Europe and US. European Pharmacopoeia, 6th ed., 2008 and Supplements 6.1 and 6.2 (Tetracycline). A yellow crystalline powder. Very slightly soluble in water; soluble …

Continue Reading...
CLOSE
CLOSE