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Tetracycline is authorised in the world under the following brand names: Abramycin, Abricycline, Achromycin, Achromycin V, Actisite, Agromicina, Ambramicina, Ambramycin, Amycin, Bio-Tetra, Biocycline, Bristaciclin, Bristaciclina, Bristacycline, Cefracycline, Ciclibion, Copharlan, Criseociclina, Cyclopar, Cytome, Democracin, Deschlorobiomycin, Dumocyclin, Enterocycline, Hostacyclin, Lexacycline, Limecycline, Liquamycin, Medocycline, Mericycline, Micycline, Neocycline, Oletetrin, Omegamycin, Orlycycline, Panmycin, Polycycline, Polyotic, Purocyclina, Resteclin, Retet, Robitet, Roviciclina, SK-Tetracycline, Solvocin, Sumycin, TAC, Tetra-CO, Tetrabon, Tetrachel, Tetracycl, Tetracycline II, Tetracyn, Tetradecin, Tetrafil, Tetramed, Tetraverine, Tetrex, Topicycline, Tsiklomistsin, Tsiklomitsin, Veracin, Vetacyclinum.

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Tetracycline: Side Effects See also Individual agents The tetracyclines are a closely related group of antibiotics with comparable pharmacological properties but different pharmacokinetic characteristics. They have both the advantages and disadvantages of broad-spectrum antibiotics. Tetracyclines are effective not only against bacteria and spirochetes, but also against some forms of Mycoplasma, Chlamydia, and Rickettsia, as well as protozoa. They affect multiplying microorganisms by inhibiting ribosomal protein synthesis. Their effect is therefore primarily bacteriostatic rather than bactericidal, depending on the kind of microorganism. Most of the adverse effects of the tetracyclines depend on the concentration of the antibiotic in the affected organ. The more lipophilic drugs are more potent with regard to their …

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Tetracycline: Drug-Drug Interactions Antacids Co-administration of tetracyclines with antacids or other drugs containing divalent or trivalent cations, such as calcium, magnesium, or iron, is contraindicated. Tetracyclines form complexes with such cations, which are very poorly or not at all absorbed. To avoid this interaction, delay of 2-3 hours between the ingestion of tetracycline and the cation is recommended. Similarly, reduced systemic availability results from simultaneous intake of abundant quantities of milk or milk products. Antidiarrheal drugs Antidiarrheal drugs, such as kaolin-pectin and bismuth products, impair the absorption of tetracyclines by chelation (see the interaction with antacids in this post). Coumarin anticoagulants Although antibiotics can inhibit the production of vitamin K in …

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Tetracycline: Organs and Systems Cardiovascular Cardiovascular reactions to tetracyclines have often been associated with other symptoms of hypersensitivity, such as urticaria, angioedema, bronchial obstruction, and arterial hypotension. Such reactions occurred in patients who had tolerated tetracyclines previously and were therefore considered as anaphylactic. Respiratory There have been a few cases of acute bronchial obstruction after the administration of a tetracycline. Pneumonitis with eosinophilia has also been described. When pleural tetracycline instillation is used to produce local inflammation for pleurodesis in spontaneous pneumothorax, there are no severe short-term or long-term adverse effects. Nervous system Tetracyclines rarely cause benign intracranial hypertension. This syndrome has primarily involved children, although it has also been observed …

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Tetracycline: General Adverse Effects Mild gastrointestinal disturbances are common. A common and nearly unique feature of all tetracyclines is the formation of drug-melanin complexes, resulting in pigment deposition at various sites. Except for enamel defects and presumable disturbances of osteogenesis these deposits do not give rise to abnormalities of organ function. In view of tooth discoloration and enamel hypo-plasia, with a tendency to caries formation, tetracyclines should be avoided in children under 8 years of age and in women after the third month of pregnancy. The risk of photosensitivity reactions largely depends on the dose of the drug and the degree of exposure to sunlight. It may be increased in long-term …

Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials. Determinants of Antimicrobial Efficacy Measurement of antimicrobial activity in vitro Susceptibility testing is indicated for any bacterial pathogen warranting chemotherapy. Drugs that irreversibly destroy the ability of an organism to replicate, and perhaps in the process destroy the structural integrity of the organism, are microbicidal. Drugs that reversibly impair replicating ability, with this function being restored when drug concentrations fall below critical inhibitory levels, are microbiostatic. In quantitative …

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Tetracycline [Sumycin 250mg, 500mg] (British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Tetraciclina; Tetraciklin; Tetraciklinas; Tetracyclinum; Tetracyklin; Tetrasykliini BAN: Tetracycline INN: Tetracycline [rINN (en)] INN: Tetraciclina [rINN (es)] INN: Tétracycline [rINN (fr)] INN: Tetracyclinum [rINN (la)] INN: Тетрациклин [rINN (ru)] Chemical name: A variably hydrated form of (4S,4aS,5aS,6S,12aS)-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide Molecular formula: C22H24N2O8 =444.4 CAS: 60-54-8 (anhydrous tetracycline); 6416-04-2 (tetracycline trihydrate) ATC code: A01AB13; D06AA04; J01AA07; S01AA09; S02AA08; S03AA02 Read code: y00qJ [Mouth]; y02NR; y08DH [Systemic] Pharmacopoeias. In Europe and US. European Pharmacopoeia, 6th ed., 2008 and Supplements 6.1 and 6.2 (Tetracycline). A yellow crystalline powder. Very slightly soluble in water; soluble …

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(US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Gentamicin Sulphate; Gentamicin sulfát; Gentamicin-szulfát; Gentamicina, sulfato de; Gentamicini Sulfas; Gentamicino sulfatas; Gentamicinsulfat; Gentamisiinisulfaatti; NSC-82261; Sch-9724 BAN: Gentamicin Sulphate [BANM] USAN: Gentamicin Sulfate INN: Gentamicin Sulfate [pINNM (en)] INN: Sulfato de gentamicina [pINNM (es)] INN: Gentamicine, Sulfate de [pINNM (fr)] INN: Gentamicini Sulfas [pINNM (la)] INN: Гентамицина Сульфат [pINNM (ru)] CAS: 1403-66-3 (gentamicin); 1405-41-0 (gentamicin sulfate) ATC code: D06AX07; J01GB03; S01AA11; S02AA14; S03AA06 Note. GNT is a code approved by the British Pharmacopoeia 2008 for use on single unit doses of eye drops containing gentamicin sulfate where the individual container may be …

Dosage forms of Tetracycline:
Tetracycline powder Tetracycline hcl powder Apo-Tetra 250 mg Capsule Tetracycline HCl 250 mg capsule
Tetracycline HCl 500 mg capsule      

Synonyms of Tetracycline:

Anhydrotetracycline, TC, Tetracycline HCl

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