Tags: Streptococcal pharyngitis

Streptococcus Pyogenes

Essentials of Diagnosis • Pharyngitis: presence of sore throat, submandibular adenopathy, fever, pharyngeal erythema, exudates. • Rheumatic fever: migratory arthritis, carditis, Syndenham’s chorea, pharyngitis. • Cellulitis: pink skin, fever, tenderness, swelling. • Scarlet fever: sandpaper-like erythema, strawberry tongue, streptococcal pharyngitis or skin infection, high fever. • Post-streptococcal glomerulonephritis: acute glomerulonephritis (hematuria, proteinuria) following pharyngitis or impetigo. • Impetigo: dry, crusted lesions of the skin, weeping golden-colored fluid. • Erysipelas: salmon red rash of face or extremity, well-demarcated border, fever, occasionally bullous lesions. • Streptococcal toxic shock syndrome: isolation of Group A streptococcus from a normally sterile site, sudden onset of shock and organ failure. • Necrotizing fasciitis, myonecrosis: deep, severe pain, …

Continue Reading...

Streptococcal Toxic Shock Syndrome

In the late 1980s, invasive GAS infections occurred in North America and Europe in previously healthy individuals of all ages. This illness is associated with bacteremia, deep soft-tissue infection, shock, multi-organ failure, and death in 30% of cases. StrepTSS occurs sporadically, although minor epidemics have been reported. Most patients present with a viral-like prodrome, history of minor trauma, recent surgery, or varicella infection. The prodrome may be caused by a viral illness that predisposed to strepTSS, or these vague early symptoms may be related to the evolving infection. In cases associated with necrotizing fasciitis, the infection may begin deep in the soft tissue at a site of minor trauma that frequently …

Continue Reading...

Order Generic Zithromax Low Cost No Prescription 250mg/500mg/1000mg

Order Generic Zithromax low cost online no prescription 250mg/500mg/1000mg See also Macrolide antibiotics Generic Zithromax (Azithromycin): Side Effects Observational studies In 3995 patients who took azithromycin 1.5 g in divided doses over 5 days or who took 1 g as a single dose for urethritis/cervicitis adverse events occurred in 12%. In patients over 65 years the rate was 9.3%, and in children under 14 years of age it was 5.4%. The most common adverse effects were gastrointestinal (9.6%); central nervous system and peripheral nervous system effects were reported in 1.3%. Overall, 59% of the adverse events were considered mild, 34% moderate, and only 6% severe, involving mainly the gastrointestinal tract. Adverse …

Continue Reading...

Respiratory Tract Infections, Upper

Otitis media Definition Otitis media is an inflammation of the middle ear. Acute otitis media involves the rapid onset of signs and symptoms of inflammation in the middle ear that manifests clinically as one or more of the following: otalgia (denoted by pulling of the ear in some infants), hearing loss, fever, or irritability. Otitis media with effusion (accumulation of liquid in the middle ear cavity) differs from acute otitis media in that signs and symptoms of an acute infection are absent. Otitis media is the most frequent diagnosis in infants and children. Risk factors contributing to increased incidence of otitis media include the winter season, attendance at a day care …

Continue Reading...

Toxicity of Antimicrobial Therapy

Mechanisms of toxicity The mechanisms associated with common adverse reactions to antimicrobials include dose-related toxicity that occurs in a certain fraction of patients when a critical plasma concentration or total dose is exceeded, and toxicity that is unpredictable and mediated through allergic or idiosyncratic mechanisms. For example, certain classes of drugs such as the aminoglycosides are associated with dose-related toxicity. In contrast, the major toxicity of the penicillins and cephalosporins is due to allergic reactions. These differences are explained in part by the relative ability of specific drugs to inhibit enzymatic pathways in the host versus their stimulation of specific immune response. Not included in these lists is mention of the …

Continue Reading...

Management of Sepsis

Definition and prognosis Sepsis, sepsis syndrome, septic shock, and multiorgan dysfunction are all part of a continuum of infection-related systemic illness. Table Definitions for Sepsis, Sepsis Syndrome, Septic Shock and Multiorgan Dysfunction Syndrome gives definitions for each of these entities. The pathogenesis of sepsis is very complex, involving a large number of mediators. A cascade is started when endotoxin or other products of microorganisms enter the circulation, resulting in the release of a variety of mediators from mononuclear phagocytes, endothelial cells and other cells. Initially the proinflammatory cytokines (tumor necrosis factor, IL-1β, IL-6, and IL-8) are elevated, although there are large individual variations. The anti-inflammatory cytokines (IL-10) and soluble cytokine receptors …

Continue Reading...

Penicillins

Penicillin G Penicillin G is an acid that is combined with sodium, potassium, procaine, or benzathine to increase its stability or to regulate its absorption. The latter two are “long-acting” forms. Penicillin G is useful in the treatment of streptococcal infections due to S. pyogenes (group A), S. agalactiae (group B), S. pneumoniae, viridans streptococci, Corynebacterium diphtheria, N. meningitidis, many strains of N. gonorrhea, Treponema pallidum, and many anaerobic streptococci, such as peptococcus and peptostreptococcus. In combination with aminoglycosides, any penicillin G compounds can be used to treat enterococci and L. monocytogenes infections. These organisms cause many clinical syndromes including cellulitis, pharyngitis, pneumonia, septicemia, endocarditis, meningitis, abscesses in lung, sexually transmitted …

Continue Reading...

Buy Cleocin (Clindamycin) Without Prescription 150/300mg

Clindamycin Hydrochloride, Clindamycin Palmitate Hydrochloride, Clindamycin Phosphate: Uses Clindamycin generally is used for the treatment of serious infections caused by susceptible gram-positive bacteria and for the treatment of serious infections caused by susceptible anaerobic bacteria. Because the risk of severe, potentially fatal Clostridium difficile-associated diarrhea and colitis may be higher with clindamycin than with certain other anti-infectives, use of the drug should be limited to serious infections for which less toxic and/or more effective anti-infectives are not readily available. However, it should be noted that C. difficile diarrhea and colitis has been associated with the use of nearly all anti-infectives, being reported most frequently with clindamycin, cephalosporins, and ampicillin; second and …

Continue Reading...

Order Augmentin (Amoxicillin) Without Prescription

Amoxicillin-Clavulanate Potassium [US: Augmentin Tablets] Generic Name: Amoxicillin & Clavulanate Under what local brands and in what dosages is generic Amoxicillin & Clavulanate sold in pharmacies of Britain, United States, and Canada? In pharmacies of the United States, Great Britain and Canada the pharmacists offer you to buy Amoxicillin & Clavulanate (according to your prescription or without a prescription) under such brand names and in such strengths and dosage forms: UK US Canada Augmentin-Duo 400/57 Co-amoxiclav 125/31.25mg/5ml Co-amoxiclav 250/62.5mg/5ml Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension Co-amoxiclav 500 mg/125 mg Tab Co-amoxiclav for Injection 500/100mg & 1000/200mg Augmentin 125mg Tablets Augmentin 200mg Tablets Augmentin 250 mg Tablets Augmentin 400 mg Tablets Augmentin 500 mg …

Continue Reading...

Penicillin V, Penicillin V Potassium

• Penicillin V is a natural penicillin antibiotic. Uses Penicillin V potassium is used for the treatment of mild to moderately severe infections caused by organisms susceptible to low concentrations of the drug or for prophylaxis of certain streptococcal infections. For specific information on the uses of penicillin V potassium, see Uses in the Natural Penicillins General Statement 8:12.16.04. Dosage and Administration • Reconstitution and Administration Penicillin V potassium is administered orally. Penicillin V potassium should not be used for the initial treatment of severe infections and should not be relied on in patients with nausea, vomiting, gastric dilatation, esophageal achalasia, or intestinal hypermotility. Although penicillin V potassium may be given …

Continue Reading...
CLOSE
CLOSE