Tags: Mycostatin

Candidiasis Mucocutaneous

Description of Medical Condition A mucocutaneous disorder caused by infection with various species of Candida. Candida is normally present, in very small amounts, in the oral cavity, gastrointestinal tract, and female genital tract. • Candida vulvovaginitis — infection on the vaginal mucosa, often associated with cutaneous vulvar involvement • Orophatyngeal candidiasis — infection of the oral cavity (“thrush”) and/or pharynx. • Candida esophagitis — usually associated with an immunosuppressed host • Gastrointestinal candidiasis — gastritis, sometimes with ulcers, usually associated with thrush. The small and large bowel can also be affected. • Angular cheilitis — fissures formed by Candida infection at the corners of the mouth. System(s) affected: Skin/Exocrine, Gastrointestinal Genetics: …

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Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials. Determinants of Antimicrobial Efficacy Measurement of antimicrobial activity in vitro Susceptibility testing is indicated for any bacterial pathogen warranting chemotherapy. Drugs that irreversibly destroy the ability of an organism to replicate, and perhaps in the process destroy the structural integrity of the organism, are microbicidal. Drugs that reversibly impair replicating ability, with this function being restored when drug concentrations fall below critical inhibitory levels, are microbiostatic. In quantitative …

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Nystatin – Antifungal Drugs

• Nystatin is an antifungal antibiotic. Uses • Candidal Infections • Cutaneous and Mucocutaneous Candidal Infections Nystatin is used orally for the treatment of intestinal candidiasis. In patients with coexisting intestinal candidiasis and vulvovaginal candidiasis, nystatin has been administered orally in conjunction with intravaginal application of an antifungal agent. While early studies provided some limited evidence that, by reducing intestinal candidal colonization, combined oral and intravaginal antifungal therapy possibly could improve the mycologic response and reduce the recurrence rate of vulvovaginal candidiasis, most evidence suggests that combined therapy does not substantially reduce the risk of recurrence compared with intravaginal therapy alone. Nystatin has been administered orally as a suspension in conjunction …

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Nystatin

Drug Approvals (British Approved Name, US Adopted Name, rINN) INNs in other languages (French, Latin, Spanish): Synonyms: Fungicidin; Nistatina; Nistatinas; Nisztatin; Nystatiini; Nystatin; Nystatinum BAN: Nystatin USAN: Nystatin INN: Nystatin [rINN (en)] INN: Nistatina [rINN (es)] INN: Nystatine [rINN (fr)] INN: Nystatinum [rINN (la)] INN: Нистатин [rINN (ru)] CAS: 1400-61-9 ATC code: A07AA02; D01AA01; G01AA01 Read code: y00qA [Mouth]; y013C [Skin]; y00Uh [Gynaecological Use]; y02UY; y08DQ [Systemic] Pharmacopoeias. In Europe, International, Japan, US European Pharmacopoeia, 6th ed. (Nystatin). An antifungal substance obtained by fermentation using certain strains of Streptomyces noursei. It contains mainly tetraenes, the principal component being nystatin A:. The potency is not less than 4400 units/mg and not less …

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