Tags: Mycobutin

Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials. Determinants of Antimicrobial Efficacy Measurement of antimicrobial activity in vitro Susceptibility testing is indicated for any bacterial pathogen warranting chemotherapy. Drugs that irreversibly destroy the ability of an organism to replicate, and perhaps in the process destroy the structural integrity of the organism, are microbicidal. Drugs that reversibly impair replicating ability, with this function being restored when drug concentrations fall below critical inhibitory levels, are microbiostatic. In quantitative …

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Rifabutin

• Rifabutin, a semisynthetic spiropiperidyl derivative of rifamycin S, is an ansamycin antibiotic that is an antimycobacterial agent. Cautions Rifabutin generally was well tolerated in controlled clinical trials. The most common adverse effects, including those that most frequently result in discontinuance of the drug, are rash, GI intolerance, and neutropenia. In controlled clinical trials in patients with severe HIV infection, adverse effects severe enough to require discontinuance occurred in 16% of patients receiving rifabutin and 8% of those receiving placebo. There is some evidence that adverse effects of rifabutin may be dose related. Because most HIV-infected patients receiving rifabutin to date have had serious underlying disease with multiple baseline symptomatology and …

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Mycobutin (Rifabutin)

Mycobutin 150mg capsules (Rifabutin) 1. What Mycobutin is and what it is used for Read indications for use if you want to order  Rifabutin online Mycobutin is an antibiotic. It is used to treat infections caused by germs (bacteria) called mycobacteria. These are bacteria which cannot be destroyed with usual antibiotics. One of the most common mycobacterial infections is Mycobacterium tuberculosis. Mycobutin can be used in combination with other antibiotics for the treatment of tuberculosis of the lung. Mycobutin can also be used to treat other mycobacterial infections such as Mycobacterium avium intracellulare (MAI, also known as MAC) or Mycobacterium xenopi. People who are unable to fight infection (such as those with …

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Tuberculosis

Description of Medical Condition A common disease transmitted by inhaling airborne bacilli from a person with active tuberculosis (TB). The bacilli multiply in the alveolus and are carried by macrophages, lymphatics and blood to distant sites (eg. lung pleura, brain, kidney and bone). Tissue hypersensitivity usually halts infection within 10 weeks. • Latent tuberculosis infection (LTBI) is asymptomatic, noninfectious and usually detected by a positive skin test • TB: active disease — occurs in 10% of infected individuals without preventive therapy. Chance of disease increases with immunosuppression and is highest for all individuals within 2 years after infection — 85% of cases are pulmonary which is infectious. • Primary TB: disease …

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