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Cestodes

Human infections caused by cestodes, or tapeworms, may occur within the lumen of the bowel, where adult cestodes attach themselves to the host intestine (Box 1). Alternatively, human infection may be the result of dissemination of cestodes from the bowel to involve extraintestinal sites, often by larval forms of the parasite. The life cycle of cestodes is determined by definitive hosts, in whom the mature adult worm lives, and intermediate hosts, which harbor the larval forms of the parasite. Humans are a definitive host for six cestodes: Diphyllobothrium latum, Taenia solium, Taenia saginata, Hymenolepis diminuta, Hymenolepis nana, and Dipylidium caninum. In addition, humans may be intermediate hosts for Echinococcus granulosis and …

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Echinococcal Infection

Essentials of Diagnosis • Radiographic finding of cyst • Positive echinococcal serology • Aspiration of cyst revealing echinococcal sand or hooks • Typical histologic appearance of cyst wall General Considerations The normal life cycle of Echinococcus species does not involve humans. Human disease occurs when humans become an accidental intermediate host for the parasite, and tissue invasion is followed by the formation of cysts (hydatid cysts). The definitive hosts for echinococcal species are canines (usually dogs), in whom the adult worms live. There may be several hundred worms within a host, and the worms are small, usually 3-6 mm long. The scolex is attached to the dog intestine, and to each …

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Cysticercosis (Cysticercus Cellulosea Infection)

Essentials of Diagnosis • Surgical excision of involved tissue, with microscopic identification of parasite. • Frequently calcified cysts present on x-ray or computed tomography (CT) scans. • Positive serology indicating previous exposure to T solium. • Fine-needle aspiration of cysts (characteristic cytomorphology). General Considerations Cysticercosis is caused by invasion of tissue by the larval forms of T solium, which have been referred to as Cysticercus cellulosea, although the name is not taxonomically correct and introduces confusion. Within a host infected by the adult T solium, eggs or proglottids are passed in the stool. Once eggs or proglottids are ingested by either pigs (intermediate hosts) or humans (definitive and intermediate hosts), eggs …

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Nematodes

Essentials of Diagnosis Intestinal nematodes: demonstration of characteristic eggs or parasites in stool. Bloodstream nematodes (filariasis): clinical diagnosis can be made; fresh blood smear may be confirmatory. Tissue nematodes: clinical diagnosis can be made; skin snip or other tissue examination may show organism. General Considerations Nematodes (roundworms) are nonsegmented, tapered, bilaterally symmetrical, cylindrical organisms that have complete digestive tracts and reproduce sexually. Although > 500,000 species of nematodes have been described, only a small number are commonly encountered as human parasites. Most nematodes have complex life cycles, sometimes involving several larval forms and intermediate hosts or free-living stages. The pathogenic nematodes may be categorized as primarily intestinal or extraintestinal tissue parasites …

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Tissue Nematode Infections

LYMPHATIC FILARIASIS Lymphatic filariasis is a bloodstream and lymphatic infection caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi, and Brugia timori. The disease is endemic in the tropics and subtropics of both hemispheres. A mosquito serves as an intermediate host and vector; the peak blood parasitemia and optimum time of the day or night for obtaining blood smears differ in various parts of the world, corresponding to the feeding pattern of the local mosquito vectors. After deposition by mosquitoes of infectious microfilariae into humans during a blood meal, 6-12 mo are required before adult worms mature and begin producing numerous circulating microfilariae to continue the life cycle. Symptoms of acute …

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Intestinal Nematode Infections

ASCARIASIS Worldwide, more than 1 billion people are infested with Ascaris lumbricoides, the causative agent of ascariasis or roundworm. More than 4 million people are estimated to be infected in the United States. Infection occurs predominately in the southeastern states and more commonly in younger children, and it is associated with lower socioeconomic status. The organism is acquired through ingestion of embryonic forms of the worm, which are found in fecally contaminated soil. After ingestion, the embryonic eggs hatch in the small intestine, and the larvae undergo a tissue migration phase. During the migration, the larvae penetrate the intestinal wall and travel intravenously to the pulmonary alveoli. In the lungs, the …

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Giardia

Essentials of Diagnosis • Key symptoms include initially profuse and watery diarrhea progressing to foul-smelling and often greasy stools that float. • It is the most common pathogen in waterborne diarrheal illness. • Patients at highest risk include infants, young children, travelers, and immunocompromised patients. • In North America, the Rocky Mountains and mountainous regions of the northwest, northeast, and British Columbia are notorious Giardia reservoirs. • Giardiasis is diagnosed either by identification of cysts or trophozoites on wet mounts of fresh stool or duodenal specimens or by antigen detection using enzyme-linked immunosorbent assay or immunofluorescence techniques. General Considerations Giardia, a genus of primitive eukaryotes, is a flagellated enteric protozoan of …

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Giardia: Clinical Syndromes

After ingestion of G lamblia cysts, 5-15% of patients will have asymptomatic cyst passage, and 25-50% of patients will have diarrhea. From 35% to 70% of these patients will have no evidence of infection. The three manifestations of infection include asymptomatic cyst passage, self-limited diarrhea, and chronic diarrhea with associated malabsorption and weight loss. Factors related to each of these manifestations are unknown but are believed to be related to specific host factors, parasite load, and virulence variation among G lamblia isolates. 1. ACUTE GIARDIASIS Clinical Findings A. Signs and Symptoms. After ingestion of cysts, an incubation period of 3-20 days exists before symptom onset. At the time of presentation, patients …

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Cryptosporidium, Cyclospora, & Isospora Species & Microsporidia

Within the last decade, the AIDS epidemic has heightened awareness of several gastrointestinal spore-forming protozoan pathogens. The genera Cryptosporidium, Isospora, and Cyclospora are members of the subclass Coccidia and phylum Apicomplexa; the microsporidia are a group of organisms belonging to the phylum Microspora. The spectrum of disease caused by these protozoans goes beyond gastrointestinal manifestations, and the significance of these protozoan infections is becoming increasingly appreciated in both immunocompromised and immunocompetent hosts. CRYPTOSPORIDIUM Essentials of Diagnosis • Key signs and symptoms include dehydration with watery diarrhea of variable quantity. • Waterborne transmission is the most common mode of oocyst transmission. • Patients at risk for person-to-person transmission include household contacts, sexual …

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Buy Albendazole (Albenza) Without Prescription 400mg

Albendazole: Side Effects See also Benzimidazoles Albendazole, a benzimidazole derivative closely related to mebendazole (qv), is used in the treatment of helminth infections, such as gastrointestinal roundworms, hydatid disease, neurocysticercosis, larva migrans cutanea, and strongyloidiasis. Provided that an adequate concentration is attained within the cyst, it is scolicidal. In high doses given for prolonged periods or cyclically, it is effective in echinococcosis, in which it is given in a dosage of 10 mg/kg/day for 4 weeks, repeated in six cycles with 2-week rest periods between each cycle, although even with this high dose only about one-third of patients enjoy a complete cure, some 70% having a partial response. Albendazole is also …

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Spanish And French Translations Of Common Medication Words:

English Spanish French
Medications Medicamentos Médicaments
Tablets Comprimidos Comprimés
Capsules Cápsulas Gélules
Pharmacies in the United States
Top 10 Pharmacy chains in the U. S. ranked by the number of pharmacists:
1 Walgreens 2 CVS 3 Walmart 4 Rite Aid 5 Kroger
6 Target 7 Kaiser Permanente 8 Sears 9 Cardinal Health 10 Dominick's
Pharmacy-led chains in the United Kingdom
Alliance Boots The Co-operative Lloyds Pharmacy
Numark Rowlands Pharmacy Superdrug

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Dosage forms of Albendazole:

Name, Strength, Form, Route
Albendazole Tablet, film coated Oral

Therapeutic classes of Albendazole:

Anthelmintics, Anticestodal Agents, Antiprotozoal Agents, Tubulin Modulators

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