Sepsis

Sepsis and Septic Shock

Definitions Physiologically similar systemic inflammatory response syndrome  can be seen even in the absence of identifiable infection. Pathophysiology The sites of infections that most frequently led to sepsis were the respiratory tract (40%), urinary tract (18%), and intra-abdominal space (14%). Sepsis may be caused by gram-negative or gram-positive bacteria, as well as by fungi or other microorganisms. Escherichia coli is the common pathogen isolated in sepsis; other common gram-negative pathogens include Klebsiella spp., Serratia spp., Enterobacter spp., and Proteus spp. Pseudomonas aeruginosa is the most frequent cause of sepsis fatality. …

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Management of Sepsis

ContentsDefinition and prognosisPathophysiologyManagement of sepsisPrevention of Perioperative InfectionsGuidelines for chemoprophylaxisPrinciples of antimicrobial prophylaxis include the following:Surgical prophylaxisPrevention of EndocarditisPrinciplesImmunoprophylaxisPrinciplesActive immunizationBuy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTCDefinition and prognosis Sepsis, sepsis syndrome, septic shock, and multiorgan dysfunction are all part of a continuum of infection-related systemic illness. Table Definitions for Sepsis, Sepsis Syndrome, Septic Shock and Multiorgan Dysfunction Syndrome gives definitions for each of these entities. The pathogenesis of sepsis is very complex, involving a large number of mediators. A cascade is started when endotoxin or other products of microorganisms enter the circulation, resulting in the release of a variety of mediators from mononuclear phagocytes, endothelial …

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Sepsis

ContentsDescription of Medical ConditionMedical Symptoms and Signs of DiseaseWhat Causes Disease?Risk FactorsDiagnosis of DiseaseDifferential DiagnosisLaboratoryPathological FindingsSpecial TestsImagingDiagnostic ProceduresTreatment (Medical Therapy)Appropriate Health CareGeneral MeasuresSurgical MeasuresActivityDietPatient EducationMedications (Drugs, Medicines)Drug(s) of ChoiceAlternative DrugsPatient MonitoringPrevention / AvoidancePossible ComplicationsExpected Course / PrognosisMiscellaneousAssociated ConditionsAge-Related FactorsPregnancySynonymsInternational Classification of DiseasesSee AlsoOther NotesBuy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTCDescription of Medical Condition The systemic response to infection; it encompasses a broad array of clinical manifestations and overlaps with inflammatory reactions to other clinical insults (e.g., severe trauma or burn) • Bacteremia: Bacteria in the blood; may have no accompanying symptoms • Systemic inflammatory response syndrome (SIRS) inflammatory reaction to different clinical insults manifest by …

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