Taenia Solium Infection

Essentials of Diagnosis

  • Spheroidal yellow-brown eggs (31-43 um).
  • Scolex has hooklets and four suckers.
  • Proglottids usually appear as short chains.
  • Mature proglottids are square and nonmotile.
  • Gravid proglottid has 7-13 lateral branches on each side of uterus.

General Considerations

T solium infection occurs worldwide; endemic areas include Mexico, South and Central America, Africa, Southeast Asia, India, and the Philippines. T solium infection is commonly linked to the ingestion of undercooked pork, although other animals may harbor the larval form of the parasite. Infection may be intestinal, which is typically asymptomatic, or extraintestinal (called cysticercosis, see below), which is caused by larval forms of T solium within the tissues of the human host. Ingestion of encysted T solium larvae is followed by the parasite scolex attaching to the intestinal mucosa, which allows the worm to grow into an adult within 12 weeks. There may be one or more adult worms present for = 25 years, and these may reach lengths of 2 to 7 m. Each worm contains < 1000 proglottids. Identification of species is by the number of lateral branches on the side of the uterus within a gravid uterus.

Taenia

Clinical Findings

A. Signs and Symptoms. Infection with the adult worm of T solium is usually asymptomatic, but nonspecific abdominal symptoms including indigestion and nausea may be present.

B. Laboratory Findings. Patients with intestinal T solium infection will frequently have abnormal results of stool examinations for ova and parasites and occasionally will have a mild leukocytosis with eosinophilia.

Differential Diagnosis

Since infection with the adult worm of T solium is asymptomatic, the main diagnostic concern in a patient with intestinal T solium is whether the patient has cysticercosis. If the results of evaluation suggest that there is extraintestinal infection, then specific therapy for cysticercosis is required.

Complications

T solium infection of the intestine is not commonly associated with symptoms; however, in patients with high parasite loads, obstruction may occur.

Taenia Solium Life Cycle

Treatment

Therapy for T solium infection of the intestine consists of either praziquantel or niclosamide (see Box 2). Follow-up examinations of stool should be performed 1 month after treatment.

Prognosis

The prognosis for patients with intestinal T solium infection is excellent.

Prevention & Control

Prevention from infection with T solium involves adequate cooking of pork and pork products to a > 65 °C core temperature (Box 3). Freezing, pickling, and salting do not prevent infection. Immunization of swine and provision of animal feed that is free of eggs and proglottids are other preventative measures that have been reported to be effective in controlling infection. Since infected humans are capable of transmitting cysticercus to others, enteric precautions should be used, and stool specimens should be handled with attention to decontamination. In addition, adequate facilities for disposal of human sewage should be available.

Buy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTC

Bactrim 400+80, 800+160 mg (Co-trimoxazole) Cipro 250, 500, 750, 1000 mg (Ciprofloxacin)
Diflucan 50, 100, 150, 200 mg (Fluconazole) Flagyl 200, 400 mg (Metronidazole) Tablets
Grifulvin 250 mg (Griseofulvin) Tablets Levaquin 250, 500, 750 mg (Levofloxacin)
Nizoral 200 mg (Ketoconazole) Tablets Sporanox 100 mg (Itraconazole) Capsules
Vermox 100 mg (Mebendazole) Tablets Zithromax 250 mg, 500 mg (Azithromycin)
CLOSE
CLOSE