Anti-Infective Therapy

Anti-Infective Therapy

ContentsKey PointsAbout Anti-Infective TherapyAntibiotic ResistanceAnti-Infective Agent DosingSpecific Anti-Infective AgentsAntifungal AgentsAntiviral Drugs (Other Than Antiretroviral Agents)Key PointsAbout Antiviral TherapyAntivirals that Block Deoxyribonucleic acid TranscriptionAcyclovir, Valacyclovir, FamciclovirKey PointsAbout Acyclovir, Valacyclovir,and FamciclovirGanciclovir and ValganciclovirKeyPoints About GanciclovirCidofovirKey PointsAbout CidofovirKey Points About FoscarnetFoscarnetOther Antiviral AgentsRibavirinKey PointsAbout RibavirinInterferonsKey PointsAbout Interferon for Treatment of Viral InfectionsAnti-influenza Viral AgentsAmantadine and RimantadineNeuramidase InhibitorsSepsis SyndromePrevalenceKey PointsAbout the Prevalence and Definitions of Sepsis SyndromeDefinitionsPathogenesisCell Wall FactorsSecreted FactorsKey PointsAbout the Bacterial Products That Cause Sepsis SyndromeHost Cell Receptors for Bacterial ProductsCytokine and Other Inflammatory Mediator CascadesHow Infection Leads to Septic ShockKey PointsAbout the Roles of Host Cells in Sepsis SyndromeClinical ManifestationsCase 1FeverHemodynamic ChangesKey PointsAbout the Clinical Manifestations of Sepsis SyndromeAcid-Base DisturbancesRespiratory ChangesDiagnosisKey PointsAbout …

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Antibiotic Drugs and Antibiotic Resistance

Genetic Modifications Leading To Antimicrobial Resistance To understand why antibiotics must be used judiciously, the physician needs to understand how bacteria are able to adapt to their environment. Point mutations can develop in the Deoxyribonucleic acid of bacteria as they replicate. These mutations occur in the natural environment, but are of no …

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Poliovirus vaccines

ContentsRubella vaccineVaricella vaccineVaricella-zoster immune globulinImmune globulinRho(D) Immune globulin (RDIg)Buy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTC Two types of trivalent poliovirus vaccines are currently licensed for distribution in the United States: an enhanced inactivated vaccine and a live attenuated, oral vaccine. inactivated vaccine is the recommended vaccine for the primary series and booster dose for children in the United States, whereas oral vaccine is recommended in areas of the world that have circulating poliovirus. inactivated vaccine is given to children aged 2, 4, and 6 to 18 months and 4 to 6 years. Primary poliomyelitis immunization is recommended for all children and young adults up to …

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Anti-Infective Agent Dosing

The characteristics that need to be considered when administering antibiotics include absorption (when dealing with oral antibiotics), volume of distribution, metabolism, and excretion. These factors determine the dose of each drug and the time interval of administration. To effectively clear a bacterial infection, serum levels of the antibiotic need to be maintained above the minimum inhibitory concentration for a significant period. For each pathogen, the minimum inhibitory concentration is determined by serially diluting the …

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Specific Anti-Infective Agents

ContentsAntibioticsβ-Lactam AntibioticsChemistry and Mechanisms of ActionKey PointsAbout b-Lactam AntibioticsToxicityKey PointsAbout β-Lactam Antibiotic ToxicityPenicillinsNatural PenicillinsKey Points About the Natural PenicillinsAminopenicillinsPenicillinase-Resistant PenicillinsKey PointsAbout the AminopenicillinsKey PointsAbout Penicillinase-Resistant PenicillinsCarboxypenicillins and UreidopenicillinsKey PointsAbout Carboxypenicillins and UreidopenicillinsCephalosporinsFirst-Generation CephalosporinsKeyPoints About First-Generation CephalosporinsSecond-Generation CephalosporinsKey PointsAbout Second-Generation CephalosporinsThird-Generation CephalosporinsKey Points About the Third-Generation CephalosporinsFourth-Generation CephalosporinsKey Points About Fourth-Generation CephalosporinsMonobactamsAztreonamKey PointsAbout AztreonamCarbapenemsChemistry and PharmacokineticsKey PointsAbout the CarbapenemsSpectrum of Activity and Treatment RecommendationsAminoglycosidesChemistry and Mechanism of ActionToxicityPharmacokineticsKey Points About Aminoglycoside ToxicitySpectrum of Activity and Treatment RecommendationsKey PointsAbout Dosing and Serum Monitoring of AminoglycosidesKey PointsAbout Aminoglycoside Antibacterial ActivityGlycopeptide AntibioticsChemistry and Mechanism of ActionToxicityKey PointsAbout Glycopeptide Antibacterial ActivityPharmacokineticsKey Points About Vancomycin ToxicityAntimicrobial Spectrum and Treatment RecommendationsMacrolides and KetolidesKey PointsAbout the Treatment Recommendations for …

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Antifungal Agents

ContentsThe Major Difference; Between Mammalian ; And Fungal CellsAgents for Treatment of Systemic Fungal InfectionsAmphotericin ВKey PointsAbout the Mechanism of Action and Spectrum of Amphotericin ВKey PointsAbout the Toxicity of Amphotericin ВKey PointsAbout Amphotericin Spectrum of Activity and PreparationsAzolesKey PointsAbout the Mechanism of Action of the AzolesKey PointsAbout Azole ToxicityKey PointsAbout the Spectrum of Activity and Indications for FluconazoleKey PointsAbout the Spectrum of Activity and Indications for ItraconazoleKey PointsAbout the Spectrum of Activity of Voriconazole and PosaconazoleCaspofungin/Anidulafungin/MicafunginKey PointsAbout the EchinocandinsFlucytosineKey PointsAbout FlucytosineBuy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTCFungi are eukaryotes, and they share many of the structural and metabolic characteristics of human cells. As a …

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