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Azithromycin is authorised in the world under the following brand names: Azenil, Azibiot, Azifine, Azitromax, Aziwok, Aztrin, Hemomycin, Misultina, Mixoterin, Setron, Sumamed, Tobil, Tromix, Vinzam, Zeto, Zifin, Zithrax, Zithromax, Zitrim, Zitrocin, Zitromax, Zitrotek, Zmax.

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1. What Zithromax 250 mg Tablets are and what they are used for

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Zithromax (azithromycin) is one of the group of macrolide antibiotics. It is used to treat a number of infections including:

• Upper and lower respiratory tract infections (eg tonsillitis, pharyngitis, sinusitis, bronchitis and pneumonia)
• Skin and soft tissue infections (eg abscesses and other infections)
• Ear infections
• Sexually transmitted diseases caused by an organism called Chlamydia (Azithromycin 500 mg Chlamydia)
  

2. Before you take Zithromax 250 mg Tablets

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Do not take Zithromax Tablets

• If you are allergic (hypersensitive) to azithromycin or to any other macrolide antibiotic (e.g. erythromycin, darithromycin), or to any of the other ingredients of Zithromax Tablets
• If you are taking any of the medicines listed under ‘Taking other medicines; Do not take’
• If you suffer from liver problems

Take special care with Zithromax Tablets

Please tell your doctor or pharmacist

• If you have severe kidney problems

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Do not take Zithromax Tablets if you are taking:

• Medicines known as ergot derivatives e.g. ergotamine or dihydroergotamine (medicines used for migraines or reducing blood flow)

It is especially important to tell your doctor or pharmacist if you are taking:

• Ciclosporin (a medicine used for skin conditions, rheumatoid arthritis, or following organ transplants)
• Theophylline (for breathing problems)
• Warfarin or other medicines to thin your blood
• Digoxin (for heart problems)
• Zidovudine (for HIV). Azithromycin may reduce the blood levels of zidovudine and should therefore be taken at least 1-2 hours before or after zidovudine
• Rifabutin (for HIV or tuberculosis)
• Terfenadine (an antihistamine)
• Antacids. Your Zithromax Tablets should be taken at least one hour before or two hours after you take your antacids

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Taking Zithromax Tablets with food and drink

You may take your medicine with or without food as it does not affect the absorption of your capsules.

Pregnancy and breast-feeding

Tell your doctor if you are pregnant, may be pregnant or are breast-feeding.

Zithromax Tablets should not be used during pregnancy or breast-feeding unless this has been discussed with your doctor. Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

Zithromax Tablets may make you feel dizzy. If affected, do not drive or operate machinery.

Important information about some of the ingredients of Zithromax (azithromycin) Tablets

This medicine contains sulphur dioxide (E220) which may rarely cause severe allergic reactions and cause difficulty in breathing.

3. How to take Zithromax (azithromycin) 250 mg Tablets

When you buy cheap Zithromax (generic: Azithromycin) you must know how to use it

Always take Zithromax (azithromycin) Tablets exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

Adults

Respiratory tract and skin or soft tissue infections: 500 mg (two capsules) once daily for three days.

Sexually transmitted diseases: 1000 mg (four capsules) as a single dose.

Elderly

The usual adult doses may be used.

Children

Zithromax Tablets are not recommended for use in children weighing less than 45 kg. For children weighing more than 45 kg the usual adult dose may be used.

Patients with kidney problems

You should make sure that your doctor knows if you have kidney problems as you may need to take a different dose or use a different medicine.

It is very important that you follow your doctor’s instructions as to the dosage of Zithromax (azithromycin) Tablets and for how long you should continue to take your capsules. Keep taking them for as long as your doctor tells you.

If you take more capsules than you should

It is important to stick to the dose on the label of your medicine. If you or someone else swallows several of these capsules all together, or you think a child has swallowed any of these capsules, contact your doctor, pharmacist or hospital emergency department immediately. Always take any capsules left over with you and also the box, as this will allow easier identification of the capsules. Symptoms of overdose may include severe nausea, vomiting and diarrhoea and reversible loss of hearing.

If you forget to take your capsules

Do not take a double dose to make up for a forgotten dose. If a dose is forgotten, it should betaken as soon as it is remembered. However, if it is nearly time for the next dose, miss the forgotten dose altogether and continue with the rest of the medicine as normal.

If you stop taking your capsules

Even when you start to feel better it is important for you to keep on taking your capsules for as long as your doctor tells you. If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side-effects

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Like all medicines, Zithromax Tablets can cause side-effects, although not everybody gets them. These are usually mild to moderate, and stop when treatment is stopped.

If you suffer from any of the following side-effects, stop taking your capsules and either tell your doctor IMMEDIATELY or go to your nearest hospital emergency department. You may be experiencing a rare severe allergic reaction to the capsules:

• Swelling of the hands, feet, ankles, face, lips, mouth or throat
• Problems with swallowing or breathing
• Serious skin reactions including Stevens-Johnson Syndrome (a severe skin rash) and other severe skin rashes which may involve blistering or peeling (these may be severe allergic reactions)
• Severe, persistent diarrhoea especially if it has blood or mucus in it (this may be Pseudomembranous colitis)

Common side effects (affecting less than 1 in 10 people):

• Feeling or being sick, stomach ache and diarrhoea

Uncommon side effects (affecting less than 1 in 100 people):

• Headache, dizziness or fits
• Allergic reactions with rashes or itching
• Taste disturbances, indigestion, inflammation of the gut, loss of appetite or wind
• Joint pain
• Vaginal infections

Rare side effects (affecting less than 1 in 1,000 people):

• Changes to the number of certain types of blood cells
• Aggressive reaction, anxiety, restlessness or nervousness
• Hyperactivity or inability to sleep
• Strange skin sensations (numbness, tingling, pins and needles or ‘burning’)
• Feeling tired or weak
• Hearing problems, hearing loss or tinnitus (ringing in the ears)
• Heart palpitations (a strong or forceful heartbeat), change in the speed of your heart beat
• Constipation, tongue discolouration
• Liver problems, hepatitis (an inflammation of the liver), jaundice (yellowing of the skin or the whites of the eyes), liver failure and liver damage
• Increased sensitivity to sunlight and sun beds, or other serious skin reactions
• Kidney damage and kidney failure
• Thrush

If any of the side effects gets serious, or if you notice any side effect not listed in this leaflet, please tell your doctor or pharmacist.

5. Further information of Zithromax (generic: Azithromycin)

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What Zithromax Tablets contain

The active substance is azithromycin. Other ingredients are cellulose microcrystalline, sodium laurilsulfate and magnesium stearate. The capsule is made of gelatin, sulphur dioxide (E220) and the colouring agents titanium dioxide (E171), FD & C Blue 2 (E132) and indigo carmine (E132).

What Zithromax (azithromycin) Tablets look like and contents of pack

These are light and dark blue capsules. Each capsule contains 250 mg of the active substance azithromycin (as azithromycin dihydrate).

Zithromax (azithromycin) 250 mg Tablets are available in packs of 2, 4, 6 or 100 capsules, although not all pack sizes may be marketed.

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