ContentsDescription of Medical ConditionMedical Symptoms and Signs of DiseaseWhat Causes Disease?Risk FactorsDiagnosis of DiseaseDifferential DiagnosisLaboratoryPathological FindingsImagingDiagnostic ProceduresTreatment (Medical Therapy)Appropriate Health CareGeneral MeasuresActivityDietPatient EducationMedications (Drugs, Medicines)Drug(s) of ChoiceAlternative DrugsPatient MonitoringPrevention / AvoidancePossible ComplicationsExpected Course / PrognosisMiscellaneousAssociated ConditionsAge-Related FactorsPregnancySynonymsInternational Classification of DiseasesSee AlsoOther NotesBuy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTCDescription of Medical Condition A mucocutaneous disorder caused by infection with various species of Candida. Candida is normally present, in very small amounts, in the oral cavity, gastrointestinal tract, and female genital tract. • Candida vulvovaginitis — infection on the vaginal mucosa, often associated with cutaneous vulvar involvement • Orophatyngeal candidiasis — infection of the oral cavity (“thrush”) …
[ Continue Reading... ]Tags: antiretrovirals
Category: Fungal Infections
Tagged in: Amphotericin, Amphotericin B, antiretrovirals, Butoconazole, Candidiasis, Canesten, Clotrimazole, Diflucan, Femstat, Fluconazole, Fungizone, Gynazole-1, Gyne-Lotrimin, Itraconazole, Ketoconazole, Lotrimin, Miconazole, Monistat, Monistat-1, Mycelex, Mycostatin, Nilstat, Nizoral, Nystatin, Retrovir, Rifampin, Sporanox, Tioconazole, Vagistat-1
ContentsPrinciplesEpidemiologic and virulence factors in infectious diseasesDocumentation of infectionAntimicrobial therapy: general principlesToxicity of Antimicrobial TherapyManagement of selected clinical conditionsNucleoside analogsNonnucleoside reverse transcriptase inhibitorsOther inhibitors of reverse transcriptaseLate-stage inhibitionProtease inhibitorsAntiretroviral resistanceGuidelines for the use of antiviral agents in human immunodeficiency virus infectionPrinciplesTreatment of human immunodeficiency virus infection in pregnancyPostexposure prophylaxisImmunomodulationVaccine strategiesPrevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency VirusNew information on management of human immunodeficiency virus infection and its complicationsManagement of the Febrile Neutropenic PatientManagement of Bacterial MeningitisManagement of Infective EndocarditisManagement of TuberculosisManagement of MalariaErythrocytic asexual phaseEvaluation of the efficacy of vaccinesEvaluation of the efficacy of vaccinesPenicillinsβ-Lactamase inhibitorsCephalosporinsMonobactamsCarbapenemsAminoglycosidesVancomycin/GlycopeptidesChloramphenicolTetracyclinesMacrolidesClindamycinMetronidazoleSulfonamides and TrimethoprimQuinolonesStreptograminsOxazolidinonesAntituberculosis DrugsAntifungal DrugsAntiviral AgentsBuy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs …
[ Continue Reading... ]Category: Diseases
Tagged in: Abdominal pain, Abscesses, Acyclovir, Aminoglycoside, aminoglycosides, Amoxicillin, Ampicillin, antiretrovirals, Azithromycin, Aztreonam, bacterial septicemia, Bacterial vaginosis, Bronchitis, Brucellosis, carbapenems, Cefotaxime, Ceftazidime, Ceftizoxime, cephalosporins, Chancroid, Chlamydia, Chloramphenicol, Cholera, Cidofovir, Cilastatin, Cipro, Ciprofloxacin, Clarithromycin, Clavulanic, Clindamycin, Crixivan, Dalfopristin, Dapsone, Delavirdine, Dexamethasone, Diarrhea, Didanosine, Doxycycline, Efavirenz, Encephalitis, Endocarditis, Ethambutol, Ethionamide, Famciclovir, Fluconazole, Fortovase, Foscarnet, Ganciclovir, Glycopeptides, Gonorrhea, Gonorrhoea, Hepatitis, Imipenem, Indinavir, Influenza, Isoniazid, Itraconazole, Ketoconazole, Lamivudine, Levofloxacin, Lincomycin, Linezolid, macrolides, Melioidosis, Meningitis, Meropenem, Methicillin, Metronidazole, Nalidixic Acid, Nelfinavir, Nevirapine, Nocardiosis, Norfloxacin, Norvir, Ofloxacin, Osteomyelitis, Otitis media, Penciclovir, penicillins, Piperacillin, Pneumonia, Probenecid, Pyrazinamide, Pyrimethamine, Quinolones, Rescriptor, Respiratory tract infections, Retrovir, Ribavirin, Rickettsial infections, Rifabutin, Rifampin, Ritonavir, Saquinavir, Shigellosis, Sparfloxacin, Stavudine, Streptomycin, Sulfadoxine, Sulfamethoxazole, Sulfonamides, Sustiva, Synercid, Tazidime, Tetracycline, tetracyclines, Ticarcillin, Trachoma, Trimethoprim, Tuberculosis, Urinary tract infections, Valacyclovir, Vancomycin, Varicella-zoster infections, Viracept, Viramune, Zidovudine
Nucleoside analog reverse transcriptase inhibitors have formed the backbone of anti-human immunodeficiency virus therapy for the last decade (see Table Characteristics of Nucleoside Reverse Transcriptase Inhibitors). Reverse transcription is necessary for human immunodeficiency virus RNA to be used as a template to produce viral DNA, which can be integrated into the cellular genome. In order for reverse transcription to take place, deoxynucleotide must be added to the end of the elongating DNA. A 3′-hydroxyl group is present on the sugar moiety of deoxynucleotides that can form a 3′,5′-phosphodiester bond allowing further addition of nucleotide triphosphates. Several deoxynucleotide analogs have …
[ Continue Reading... ]Category: Drug Guide
Tagged in: Abacavir, antiretrovirals, Combivir, Complex, Diarrhea, Didanosine, Epivir, Lamivudine, Pancreatitis, Retrovir, Stavudine, Videx, Zerit, Ziagen, Zidovudine
Contents• Adverse Effects• HIV Protease Inhibitors• Dermatologic and Sensitivity ReactionsBuy Most Popular Antibiotic, Antifungal, Antiparasitic, Antiviral Drugs Online no RX & OTCAbacavir Sulfate, Amprenavir, Atazanavir Sulfate, Delavirdine Mesylate, Didanosine, Efavirenz, Emtricitabine, Enfuvirtide, Indinavir Sulfate, Lamivudine, Lopinavir and Ritonavir, Nelfinavir Mesylate, Nevirapine, Ritonavir, Saquinavir, Stavudine, Tenofovir Disoproxil Fumarate, Zalcitabine, Zidovudine • Laboratory Monitoring • Plasma HIV-1 RNA Levels and CD4+ T-cell Counts Decisions regarding when to initiate or modify antiretroviral therapy should be guided by monitoring plasma HIV-1 RNA levels (viral load), CD4+ T-cell counts, and the clinical condition of the patient. Although various other surrogate markers and laboratory parameters were used in the past to assess the risk of progression of …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: Abacavir, Abdominal pain, antiretrovirals, Atazanavir, Atazanavir Sulfate, Complex, Delavirdine, Diarrhea, Didanosine, Efavirenz, Emtricitabine, Enfuvirtide, Hepatitis, Indinavir, Lamivudine, Lopinavir, Nelfinavir, Nevirapine, Pancreatitis, Pneumonia, Retrovir, Ritonavir, Saquinavir, Stavudine, Tenofovir, Tuberculosis, Zidovudine
Consideration should be given to altering the initial antiretroviral regimen in HIV-infected pediatric patients if there is clinical, immunologic, or virologic evidence of disease progression; if there are signs of toxicity or intolerance; or if new data become available indicating that a drug or regimen is superior to the current regimen. Clinical events that may indicate disease progression in an HIV-infected child and warrant consideration of a change in antiretroviral therapy include progressive neurodevelopmental deterioration or growth failure (i.e., persistent, unexplained decline in weight growth velocity despite adequate nutritional support). Progressive neurodevelopmental deterioration is defined as persistence or progression …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: antiretrovirals, Nevirapine, Retrovir, Zidovudine
• Patient Compliance Patient compliance with recommended regimens (even when asymptomatic) is essential to the potential benefits of antiretroviral therapy. Adherence to antiretroviral regimens is an important determinant of both the degree and duration of virologic suppression. Excellent adherence has been shown to increase the likelihood of sustained virologic control, which is important for reducing HIV-associated morbidity and mortality. Poor adherence has been shown to increase the likelihood of virologic failure and can lead to the development of resistance and limit the effectiveness of antiretroviral therapy. There is evidence that nonadherence in patients receiving HAART is the strongest predictor …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: Abacavir, antiretrovirals, Atazanavir, Combivir, Complex, Delavirdine, Didanosine, Efavirenz, Emtricitabine, Enfuvirtide, Fosamprenavir, Indinavir, Lamivudine, Lopinavir, Nelfinavir, Nevirapine, Retrovir, Ritonavir, Saquinavir, Stavudine, Tenofovir, Trizivir, Zidovudine
• Drug Interactions Among the Antiretroviral Agents While further study is needed, data are accumulating regarding pharmacokinetic interactions among the various antiretroviral agents, especially those involving the HIV protease inhibitors and NNRTIs, and the need for dosage adjustments as a result of these interactions. While some pharmacokinetic interactions between antiretroviral agents can be used for therapeutic advantage (e.g., use of low-dose ritonavir to boost plasma concentrations of some other HIV protease inhibitors), other interactions can result in suboptimal drug concentrations and reduced therapeutic effects and should be avoided. The pharmacokinetic interaction between ritonavir and other HIV protease inhibitors is …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: Abacavir, antiretrovirals, Atazanavir, Complex, Efavirenz, Indinavir, Kaletra, Lopinavir, Nelfinavir, Nevirapine, Retrovir, Rifabutin, Rifampin, Ritonavir, Saquinavir, Tuberculosis
The fact that hyperglycemia, new-onset diabetes mellitus, exacerbation of preexisting diabetes mellitus, and diabetic ketoacidosis have occurred in HIV-infected individuals receiving HIV protease inhibitors should be considered when these drugs are used during pregnancy. Because pregnancy is itself a risk factor for hyperglycemia and it is not known whether use of an HIV protease inhibitor exacerbates this risk, glucose concentrations should be monitored closely in pregnant women receiving these drugs and these women should be advised about the warning signs of hyperglycemia and diabetes (e.g., increased thirst and hunger, unexplained weight loss, increased urination, fatigue, dry or itchy skin). …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: Abacavir, antiretrovirals, Atazanavir, Atazanavir Sulfate, Bites, Combivir, Delavirdine, Diarrhea, Didanosine, Efavirenz, Hepatitis, Indinavir, Lamivudine, Lopinavir, Nelfinavir, Nevirapine, Ophthalmic, Retrovir, Ritonavir, Saquinavir, Stavudine, Zidovudine
Since most occupational exposures to HIV do not result in transmission of the virus, the potential toxicity of PEP regimens must be considered carefully and, whenever possible, prophylaxis should be implemented in consultation with clinicians who have expertise in antiretroviral therapy and HIV transmission. Modification of the recommended regimens may be appropriate based on factors such as whether the source patient is known or suspected of being infected with drug-resistant strains of HIV; the local availability of antiretroviral agents; and the medical condition, concurrent drug therapy, and drug toxicity in the exposed health-care worker. The CDC has made the …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: Abacavir, antiretrovirals, Bacterial vaginosis, Chlamydia, Didanosine, Efavirenz, Gonorrhea, Hepatitis, Indinavir, Lamivudine, Nelfinavir, Retrovir, Stavudine, Zidovudine
Safety and efficacy of zidovudine in pregnant women have been established and the drug appears to be well tolerated during pregnancy. In addition to zidovudine, data are available from clinical trials in pregnant women for didanosine, lamivudine, and stavudine; data regarding use of abacavir or tenofovir disoproxil fumarate (a nucleotide reverse transcriptase inhibitor) are not available to date. Follow-up of uninfected children born to women enrolled in study PACTG 076 (from birth to a median age of 4.2 years) has not revealed any difference in growth, neurodevelopment, or immunologic status among infants born to women who received zidovudine for …
[ Continue Reading... ]Category: Antiviral agents
Tagged in: Abacavir, antiretrovirals, Didanosine, Hepatitis, Lamivudine, Nevirapine, Retrovir, Stavudine, Tenofovir, Zidovudine
